What are the current recommendations and dosing amount/duration for treating with oral Prednisone in active/chronic childhood and adult asthmatics with exacerbations most likely due to molds (Florida late winter & early spring) . non-productive paroxysmal cough and wheeze not responding to inhaler (Advair type combo and/or inhaled steroid) and anti-histamines and recently treated and/or failure to resolve with Antbx?
In a patient as described above (no relief with inhaled treatments and anti-histamines/Leukotriene inhibitor) what levels can be used for IgE? Total to initiate Oral Steroids, I've seen a local Pulmonologist recommend adding Oral Steroids when the Ige total is above 500. Is there a reference for this? It has worked on our patients we have referred to them and they initiated that treatment type recommendation and protocol. Also they used Ige total greater than 200 for ABPA patients to start treatment.
The most commonly reported side effects were: oral thrush , nausea , headache , and pain in the pharynx or larynx . More rarely reported side effects (occurring in <1% of patients during the clinical trial) include: tachycardia , palpitations , dry mouth , allergic reaction ( bronchospasm , dermatitis , hives ), pharyngitis , muscle spasms , tremor , dizziness , insomnia , nervousness , and hypertension . Patients experiencing an allergic reaction or increase in difficulty breathing while using this medication should immediately discontinue its use and contact their physician.