Triamcinolone Acetonide: Triamcinolone acetonide is a synthetic corticosteroid. Corticosteroids are hormones that are produced naturally by the body. This class of compounds contains the most potent anti-inflammatory drugs available to us. They work by inhibiting certain reactions in cells that are responsible for causing allergic responses and inflammation. Triamcinolone acetonide is a potent and long lasting version of a corticosteroid. Unfortunately, prolonged exposure to corticosteroids can cause high intraocular pressure and induce cataract formation.
Toxic glaucoma is open angle glaucoma with an unexplained significant rise of intraocular pressure following unknown pathogenesis. Intraocular pressure can sometimes reach 80 mmHg (11 kPa). It characteristically manifests as ciliary body inflammation and massive trabecular o edema that sometimes extends to Schlemm's canal . This condition is differentiated from malignant glaucoma by the presence of a deep and clear anterior chamber and a lack of aqueous misdirection. Also, the corneal appearance is not as hazy. A reduction in visual acuity can occur followed neuroretinal breakdown.