Sitavig (acyclovir) buccal tablet was approved by the . Food and Drug Administration (FDA) in April 2013 to treat recurrent cold sores in adults with a healthy immune system. One tablet is applied as a single 50 mg dose to the upper gum regionabove one of the incisors. The medication should be applied within an hour after the onset of symptoms (., tingling sensation) on the same side as the tingling before cold sores appear . It should be held in place for about 30 seconds to ensure adhesion. Side effects are usually minor and include pain at the site of application and headache.
Our first regular contributor, the heart specialist Peter Libby, comes to grips with the issues like the "kerfuffle" over cholesterol. And he offers an insider’s view of the way researchers work — not as solitary drudges, but as a lively, talkative community whose debates may sometimes contribute to public uncertainty over medical issues.
Dr. Libby is professor of medicine at Harvard Medical School and chief of cardiovascular medicine at Brigham and Women’s Hospital in Boston. His influential studies have helped explain how inflammation contributes to atherosclerosis. Read more about Dr. Libby's affiliations and industry relationships .
If a person is experiencing symptoms orally, we recommend abstaining from performing oral sex and kissing others directly on the mouth until signs have healed and the skin looks normal again. Because most adults have oral herpes, we do not advise that a person stop giving or receiving affection altogether between outbreaks (when there are no signs or symptoms) simply because they have oral herpes. However, using a barrier (such as a dental dam) or condom when performing oral sex (even though there are no symptoms present around the mouth) can reduce the risk of contracting genital herpes.